Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly

Recruiting now · Not applicable

Conditions studied: Sarcopenia, Sarcopenia in Elderly

In brief

Population aging has become a significant global concern, and Taiwan is set to officially enter the "super-aged society" in 2025. As individuals age, various physiological functions gradually decline, including a reduction in muscle mass, which is a key aspect of the aging process. This interventional study aims to investigate the effects of leucine-rich protein combined with polyunsaturated fatty acid supplementation on middle-aged and elderly individuals (aged 50 and above) who are at high risk for sarcopenia.

Key facts

Study ID

NCT06991855

Run by

Chang Gung Memorial Hospital

People needed

90

Starts

2025-07-01

Expected to finish

2026-04-17

Last updated by the study team

2025-06-22

Who can join

Age: 50 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 50 years
• ASMI < 7 kg/m2 in men
• ASMI < 5.7 kg/m2 in women
• Grip strength < 28 kg in men
• Grip strength < 18 kg in women
• Walk speed < 1 m/s

You may not qualify if…

• People who are allergic to supplements
• cancer
• heart failure
• kidney disease
• autoimmune disease
• neurodegenerative disease

Where it is running

• Chang Gung Memorial Hospital — Linkou District, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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