Smart Measurement of Circulating Tumor DNA

Recruiting now · Not applicable

Conditions studied: Colorectal Neoplasms, Colorectal Neoplasms Malignant, Colorectal Neoplasms, Hereditary Nonpolyposis, Hereditary Nonpolyposis Colon Cancer

In brief

The goal of this study is to develop a blood-test which can detect colorectal cancer in early stages. Participants will be asked to take an extra blood test, which will be analyzed further in the lab.

Key facts

Study ID

NCT06989814

Run by

Erasmus Medical Center

People needed

50

Starts

2025-05-16

Expected to finish

2027-02-01

Last updated by the study team

2025-08-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• (suspect) Lynch Syndrome carriers who:
• Have proven Lynch Syndrome (MMR-gene or EPCAM mutation), or have a proven microsatellite instability high (MSI-H)tumor;
• Are at least 18 years old; Have been diagnosed with any form of cancer at the time of inclusion, but have had no treatment yet;
• Have granted informed consent to participate in this study.

You may not qualify if…

• (suspect) Lynch Syndrome carriers who:
• Are unwilling to undergo extra blood sampling;
• Are under the age of 18;
• Have no newly diagnosed tumors at time of inclusion;
• Have been treated for their tumor at time of inclusion;
• Are not able to read or understand Dutch language or are mentally not capable.

Where it is running

• Erasmus MC — Rotterdam, South Holland, Netherlands (enrolling)
• Leiden University Medical Center — Leiden, South Holland, Netherlands

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.