Efficacy of Routine Saline Flushing in the Prevention of Nephrostomy Tube Obstructions: A Pilot Study

Recruiting now · Not applicable

Conditions studied: Nephrostomy

In brief

The investigators performing this research to study if routine flushing is necessary to prevent obstructions of a nephrostomy tube. This study will evaluate patients that have nephrostomy tube or will have nephrostomy tubes placed as part of their standard clinical care. If participants agree to participate in this study, participants will undergo randomized assignment to either continue to routinely flush the nephrostomy tube with normal saline or not to routinely flush the nephrostomy tube with normal saline. Participantswill be in the study for approximately 3 months if they decide to stay for the whole study.

Key facts

Study ID

NCT06987877

Run by

Brigham and Women's Hospital

People needed

20

Starts

2026-01-01

Expected to finish

2027-03-30

Last updated by the study team

2026-02-06

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-80, with planned nephrostomy tube exchange or new nephrostomy tube placement with ongoing need for a nephrostomy tube.

You may not qualify if…

• Current local infection
• History of anaphylaxis to iodinated contrast
• Pregnant or intent to become pregnant during the study
• Irreversible coagulopathy
• Planned for definitive treatment for the clinical indication of the nephrostomy tube prior to 12-week post-intervention.
• Planned routine exchange prior to 12 weeks after nephrostomy tube exchange or placement procedure
• Complete sensory loss below T10 dermatome.

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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