Addressing Hypertension Care in Africa Program

Recruiting now · Not applicable

Conditions studied: Hypertension, High Blood Pressure

In brief

The ADHINCRA Program is a bundle of multilevel evidence-based interventions that address multiple predictors of controlled hypertension, including patient-, provider-, and health system-level factors. The successful implementation of the ADHINCRA program will provide a rigorous and scalable model for improving hypertension control in Africa, which would ultimately reduce the risk of cardiovascular disease, stroke and kidney disease.

Key facts

Study ID

NCT06986590

Run by

Johns Hopkins University

People needed

800

Starts

2026-01-09

Expected to finish

2028-09-01

Last updated by the study team

2026-01-14

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 18 -70 years.
• Diagnosis of hypertension and elevated systolic blood pressure measure (≥140 mmHg) on the most recent clinic visit without a diabetes diagnosis.
• Hypertension treatment naive or on monotherapy.
• Receives primary care at one of the participating sites.
• Willing and able to provide informed consent in English, Twi, Dagbani, Ewe, Hausa, or Yoruba.
• Owns a smartphone (Android or iOS).

You may not qualify if…

• Age <18 years or >70 years.
• Severely elevated BP (≥180/110mmHg).
• Diagnosis of stroke, coronary artery disease, or kidney disease.
• Diagnosis of end-stage renal disease (ESRD) treated with dialysis.
• Serious medical condition which either limits life expectancy or requires active management (e.g., cancer).
• Cognitive impairment or other conditions preventing study participation
• Pregnant or currently nursing a child
• Unwilling to provide informed consent

Where it is running

• St. John of God Catholic Hospital — Duayaw Nkwanta, Bono, Ghana (enrolling)
• Northern Regional Hospital — Tamale, Northern Region, Ghana (enrolling)
• Akure South Hospital — Akure, Ondo State, Nigeria (enrolling)
• Manhyia Government Hospital — Kumasi, Ashanti Region, Ghana (enrolling)
• Berekum Holy Family Hospital — Berekum, Bono, Ghana
• Tamale Teaching Hospital — Tamale, Northern Region, Ghana
• Ho Municipal Hospital — Ho, Volta Region, Ghana
• South Tongu District Hospital — Sogakope, Volta Region, Ghana
• Akoko North East — Ondo, Ondo State, Nigeria
• Akoko North West — Ondo, Ondo State, Nigeria
• Akoko South East — Ondo, Ondo State, Nigeria
• Akoko South West — Ondo, Ondo State, Nigeria
• Johns Hopkins University — Baltimore, Maryland, United States
• Owo General Hospital — Owo, Ondo State, Nigeria
• Dominase SDA Hospital — Bekwai, Ashanti Region, Ghana
• Kumasi South Hospital — Kumasi, Ashanti Region, Ghana
• Tafo Government Hospital — Tafo, Ashanti Region, Ghana

Full record on ClinicalTrials.gov

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