Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals

Recruiting now · Not applicable

Conditions studied: Pre Diabetes

In brief

The purpose of this study is to investigate the effect of mango intake on metabolic and inflammatory responses relative to meals in individuals at risk of developing diabetes, as well as to understand how the beneficial compounds found in mangoes are absorbed and processed in the body.

Key facts

Study ID

NCT06986161

Run by

Clinical Nutrition Research Center, Illinois Institute of Technology

People needed

30

Starts

2025-04-14

Expected to finish

2026-12-31

Last updated by the study team

2025-07-11

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Be between 20-60 years old.
• Have a BMI of 25-35 kilograms per square meter.
• Have fasting blood glucose between 100-125 milligrams per deciliter or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
• Be non-smokers for at least 12 months.
• Be generally healthy, with no major organ-related diseases.
• Not take medications or supplements that could interfere with the study.
• Be able to follow study procedures, including dietary restrictions and scheduled visits.

You may not qualify if…

• Smoke, vape, or use marijuana.
• Have allergies or intolerance to mangoes or study foods.
• Have blood pressure above 160/100 millimeters of Mercury.
• Have fasting blood glucose above 125 milligrams per deciliter.
• Have a history of major heart disease, stroke, or cancer in the past five years.
• Be pregnant, planning to become pregnant, or breastfeeding.
• Take anti-inflammatory drugs or certain dietary supplements.
• Have had major surgery or trauma in the past two months.
• Follow extreme diets (e.g., vegan, Atkins).
• Have used antibiotics in the last six weeks.
• Have a history of eating disorders or substance abuse in the past two years.
• Drink more than three cups of coffee or tea per day.
• Have donated blood in the last three months.
• Be professional athletes or do excessive exercise.
• Have had weight changes of more than 11 pounds in the past two months.
• Work overnight shifts.

Where it is running

• Clinical Nutrition Research Center — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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