Genetic Markers of Diabetic Ulcers and Personalized Treatment Targets Research
Recruiting now
Conditions studied: Diabetic Ulcers
In brief
This clinical trial involves collecting peripheral blood, ulcer tissue, and fecal samples from diabetic ulcer patients for bioinformatics analysis to screen genetic markers significantly associated with ulcer risk and healing differences. Furthermore, multi-omics data will be integrated to establish a diabetic ulcer risk prediction model. Based on key single nucleotide polymorphisms and their regulatory pathways, potential new drug targets for promoting healing will be explored, providing a genetic basis for personalized treatment.
Key facts
- Study ID
- NCT06979037
- Run by
- The First Affiliated Hospital of University of South China
- People needed
- 712
- Starts
- 2024-05-16
- Expected to finish
- 2027-05-16
- Last updated by the study team
- 2025-05-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 1) Subjects who voluntarily participate in this clinical study and sign informed consent;
- 2) Patients with type 2 diabetes and diabetic ulcers;
- 3) Disease duration ≥ 10 years or age ≥ 55 years at enrollment;
- 4) Inpatient or outpatient who can be monitored by the same investigating team throughout the duration of the study.
You may not qualify if…
- 1) Severe vascular occlusion or impairment;
- 2) Patients with congenital heart disease, aortic dissection, or other severe cardiovascular diseases;
- 3) Patients with ulcers caused by factors other than diabetes;
- 4) Patients with severe liver and kidney dysfunction or serious neurological impairment.
Where it is running
- The First Affiliated Hospital of University of South China — Hengyang, Hunan, China (enrolling)
Full record on ClinicalTrials.gov
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