Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain

Recruiting now · Not applicable

Conditions studied: Chronic Pain, Depression, Anxiety

In brief

The purpose of this research study is to refine customized in-app notifications in order to optimize users' experience with a mobile app called Wysa for Chronic Pain. This app is designed to support people who have chronic pain and who also experience symptoms of depression and/or anxiety. This version of the app is not currently available to the public. Eligible participants will be asked to download and use the Wysa for Chronic Pain study app for several weeks, and to use it as they normally would if they were not part of a research study. At the beginning and end of the study period, participants will be asked to complete brief surveys about their mood, pain, physical function, and sleep. Additionally, a few participants will be asked to share their experience with the study app at the end of the research study in a casual interview using a secure audio/video recorded call. Participating in the interview portion is optional.

Key facts

Study ID

NCT06978166

Run by

Washington University School of Medicine

People needed

1000

Starts

2025-06-02

Expected to finish

2026-12-01

Last updated by the study team

2026-05-05

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 45 years or older
• At least moderately severe depression and/or anxiety symptoms (Patient Health Questionnaire-9 (PHQ-9) and/or Generalized Anxiety Disorder-7 (GAD-7) score ≥ 10)
• Chronic pain (i.e., pain on most days or every day in the past three months)

You may not qualify if…

• Frequent active suicidal ideation
• No access to a mobile device
• Not living in the United States

Where it is running

• Washington University in St. Louis School of Medicine — St Louis, Missouri, United States (enrolling)

Full record on ClinicalTrials.gov

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