Symptoms, Pulmonary Function, Muscle Strength, Exercise Capacity, and Frailty in Esophageal Atresia vs. Healthy Peers
Recruiting now
Conditions studied: Esophageal Atresia, Healthy Children
In brief
Esophageal atresia is the most common congenital anomaly of the esophagus and is caused by abnormal development of the esophagus during intrauterine life. In children with esophageal atresia, structural abnormalities due to congenital anomalies and tracheoesophageal fistula, tracheomalacia, respiratory problems, recurrent respiratory tract infections, structural abnormalities, surgical interventions for repair and treatment, and decreased physical activity levels may negatively affect pulmonary function, effective coughing, muscle strength, exercise capacity, posture, motor function, and quality of life. This study aims to compare physical characteristics, body composition, pulmonary function and muscle strength, peak cough flow, posture assessment, peripheral muscle strength test, motor function, exercise capacity, physical activity level, fatigue, frailty and quality of life between children with esophageal atresia and their healthy peers.
Key facts
- Study ID
- NCT06975982
- Run by
- Hacettepe University
- People needed
- 20
- Starts
- 2024-10-24
- Expected to finish
- 2027-10-24
- Last updated by the study team
- 2025-05-29
Who can join
Age: 6 and older, up to 18. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Children with esophageal atresia who are willing to participate in the study
- Being between the ages of 6-18,
- Being able to cooperate with the assessments
You may not qualify if…
- Being unable to cooperate with the assessments,
- Having an orthopedic, neurological or cardiovascular problem that may affect the assessments,
- Having a lung infection or upper respiratory tract infection in the last four weeks,
- Being an active smoker,
- Not being willing to participate in the study,
- Control group
- Inclusion Criteria:
- Being between the ages of 6-18,
- Being willing to cooperate with the tests to be performed,
- Being willing to participate in the study.
- Exclusion Criteria:
- Having a musculoskeletal problem that may affect exercise performance,
- Having any known chronic disease,
- Having a lung infection or upper respiratory tract infection in the last four weeks,
- Being an active smoker,
- Not willing to participate in the study.
Where it is running
- Hacettepe University Faculty of Physical Therapy and Rehabilitation — Ankara, Ankara, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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