Resilience to Antibiotic-induced Obesogenic Microbiota: Discovering Mechanism of Microbiota Modulation

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Healthy Newborn Infants

In brief

The aim is to study whether the microbiota of children who are exposed to antibiotics at birth could be modified by synbiotic supplement and thereby reduce the risk of obesity, chronic diseases and respiratory tract infections. A total of 125 mother-child pairs will be recruited in this randomized, double-blind, placebo-controlled study. Infants are randomized to receive either a synbiotic supplement or a placebo for 2 months, after which their growth and morbidity will be monitored at the research clinic for 2 years.

Key facts

Study ID

NCT06974994

Run by

Turku University Hospital

People needed

125

Starts

2024-05-08

Expected to finish

2029-12-01

Last updated by the study team

2025-05-16

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Pregnant women (n=125) and their newborn children who receive antibiotic treatment at delivery.

You may not qualify if…

• Chorioamnionitis
• Pre-eclampsia and hepatogestosis
• Suspected malformation or serious condition of the foetus and neonates
• Serious infection or other conditions not permitting breast milk feeding

Where it is running

• Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku — Turku, Valitse Maakunta., Finland (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.