Post-Stroke Aphasia TMS

Recruiting now · Not applicable

Conditions studied: Aphasia, Stroke, Language

In brief

The investigator proposes to examine the effects of excitatory transcranial magnetic stimulation (TMS) combined with semantic feature analysis (SFA) language therapy to improve word-finding abilities in stroke survivors with aphasia (SWA).

Key facts

Study ID

NCT06974279

Run by

Medical College of Wisconsin

People needed

50

Starts

2025-09-01

Expected to finish

2036-12-31

Last updated by the study team

2026-07-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with left hemisphere stroke
• Consent date >= 1 month after stroke onset
• Fluent in English
• 18 years of age or older

You may not qualify if…

• Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing
• Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease)
• A chronic medical condition that is not treated or is unstable
• The presence of cardiac stimulators or pacemakers or intracardiac lines, neurostimulators, medication infusion device, any other implants near the scalp (e.g., cochlear implants) or in the eye, metal in the body (e.g., splinters, fragments, clips)
• Pregnancy
• History of skull fractures, or skin diseases
• History of ongoing or unmanaged seizures
• Presence of factors that potentially decrease seizure thresholds: on pro-convulsant medications, untreated sleep deprivation or insomnia, ongoing alcoholism or illegal drug abuse (e.g., cocaine or MDMA users)
• History of dyslexia or other developmental learning disabilities

Where it is running

• Medical College of Wisconsin — Milwaukee, Wisconsin, United States (enrolling)

Full record on ClinicalTrials.gov

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