Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Depression, Unipolar
In brief
This study examines the efficacy of bright light therapy as a treatment for adolescents diagnosed with unipolar non-seasonal depression who exhibit an evening chronotype.
Key facts
- Study ID
- NCT06973759
- Run by
- Chinese University of Hong Kong
- People needed
- 90
- Starts
- 2025-11-01
- Expected to finish
- 2028-06-30
- Last updated by the study team
- 2026-03-19
Who can join
Age: 12 and older, up to 19. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Chinese, aged 12-19 years old;
- Written informed assent/consent of participation into the study is given by the participant and his/her parent or guardian (for those aged under 18), respectively;
- Having a DSM-5 diagnosis of unipolar non-seasonal depression as confirmed by the Chinese version of the Kiddie-Schedule for Affective Disorders and Schizophrenia (K-SADS) psychiatric interview, DSM-5 Seasonal specifier, AND having a score on Children's Depression Rating Scale (CDRS-R) at least 40;
- Being classified as evening chronotype according to the score on the reduced Horne-Östberg Morning-Eveningness Questionnaire (rMEQ), i.e. <12.
You may not qualify if…
- A current diagnosis of substance abuse or dependence; a current or past history of manic or hypomanic episode, schizophrenia spectrum disorders, organic mental disorders, or intellectual disabilities;
- Having a clinically significant suicidality (presence of suicidal ideation with a plan or an attempt) as assessed by K-SADS;
- Having been enrolled in any other clinical trial investigational products within one month at the entry of the study;
- Initiation of or change in antidepressant medication within past 4 weeks;
- Having been or is currently receiving any structured psychotherapy;
- With hearing or speech deficit;
- Night shift worker;
- Trans-meridian flight across at least two time zones in the past 3 months and during the study;
- Presence of an eye disease, e.g., retinal blindness, severe cataract, glaucoma.
Where it is running
- The Chinese University of Hong Kong — Hong Kong, Hong Kong, Hong Kong (enrolling)
Full record on ClinicalTrials.gov
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