INDUCE: A Prospective 2-Year Spine Registry
Enrolling by invitation
Conditions studied: Subjects Treated With NMP as Part of Their Spine Surgery, Degenerative Disc Disease (DDD)
In brief
The primary objective of this prospective, observational registry study is to evaluate the safety and effectiveness of Natural Matrix Protein® (NMP®) when used to promote fusion in the cervical or lumbar spine. The secondary objective is to assess patient reported outcomes following the use of NMP in the treatment of the spine.
Key facts
- Study ID
- NCT06971835
- Run by
- Red Rock Regeneration Inc.
- People needed
- 1000
- Starts
- 2026-02-17
- Expected to finish
- 2029-01-01
- Last updated by the study team
- 2026-04-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Implanted on-label with NMP in at least one vertebral level in the cervical (C1-C7) or lumbar (L1-S1) spine as part of their surgery
- Total volume of bone graft or bone graft substitute used in index surgery must contain at least 50% NMP by volume per treated level, where NMP is mixed with other graft material.
- Skeletally mature (age≥18 years of age)
- Be willing to sign the study-specific informed consent document prior to index surgery
You may not qualify if…
- Not willing to sign the study-specific informed consent document prior to index surgery
- Use of allogenic growth factor extacts (i.e. OsteoFactor/ProteiOS) or cell based allografts as part of the index surgery (use of autograft or bone marrow aspirate (BMA) is allowed)
- Use of rhBMP-2 (i.e. INFUSE) or synthetic peptide enhanced graft (i.e. iFactor) as part of the index surgery
- Diagnosis of spinal deformity (greater than 20 degrees) or vertebral fracture including treated level
- Unable to comply with postoperative standard of care imaging (e.g. pregnant or nursing female)
- Did not complete baseline patient reported outcomes prior to index surgery
- Incarcerated at the time of surgery or preoperative evaluation
Where it is running
- Spine Center of Louisiana — Baton Rouge, Louisiana, United States
- Spine Institute of Louisiana — Shreveport, Louisiana, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.