Perfusion Index in Pediatric Low-Flow Anesthesia

Recruiting now · Not applicable

Conditions studied: Perfusion Index, Low-Flow Anesthesia, Postoperative Recovery

In brief

This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia. PI will be monitored at multiple intraoperative and postoperative time points to assess its relationship with hemodynamic stability and depth of anesthesia. The study will also investigate whether low-flow anesthesia affects the incidence of emergence agitation (EA). Patients will be assigned to either low-flow or normal-flow anesthesia groups based on routine clinical practice. No intervention will be applied beyond standard care. The findings are expected to provide insight into the predictive value of PI in postoperative recovery and support safer anesthesia practices in pediatric populations.

Key facts

Study ID

NCT06967675

Run by

Istinye University

People needed

90

Starts

2025-06-15

Expected to finish

2025-08-10

Last updated by the study team

2025-07-10

Who can join

Age: 2 and older, up to 12. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ASA I-II pediatric patients
• Age 2 to 12 years
• Undergoing elective surgery lasting between 1-6 hours
• Informed consent obtained from parents/guardians

You may not qualify if…

• Cardiovascular, respiratory, neurological, metabolic, or endocrine disorders
• Premature birth with corrected age < 2 years
• Obesity or severe malnutrition (BMI <5th or >95th percentile)
• Psychiatric or neurodevelopmental disorders (e.g., autism)
• Malignant hyperthermia or hypersensitivity to anesthetics
• Emergency surgeries
• Lack of IV access requiring inhalational induction
• Contraindications to low-flow anesthesia including:
• Severe pulmonary disease
• Congenital heart disease with shunt physiology
• Anticipated high oxygen demand
• Airway obstruction risk
• Surgeries requiring high gas flow or >6 hours duration

Where it is running

• Istinye Üniversity — Istanbul, Merkez Mahallesi, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.