Respiratory Virus Infections in Acute Heart Failure
Recruiting now
Conditions studied: Acute Heart Failure Syndrome
In brief
Patients admitted to the cardiology department with acute heart failure who have a nasopharyngeal respiratory virus PCR test performed within 72 hours of admission will be enrolled in the study cohort. The detection rate of respiratory viruses including influenza virus, RSV, and coronavirus will be analysed. The investigators will also look for seasonal changes in the frequency of respiratory viruses and differences in the clinical presentation of heart failure based on respiratory virus infection.
Key facts
- Study ID
- NCT06967441
- Run by
- Minjae Yoon
- People needed
- 360
- Starts
- 2025-04-07
- Expected to finish
- 2028-12-31
- Last updated by the study team
- 2026-03-11
Who can join
Age: 19 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult aged 19 years or older admitted to the cardiology department with acute heart failure
- NT-proBNP >300 pg/mL
- Clinician judgement of possible respiratory viral infection (fever >38 degrees or cough, respiratory symptoms such as sputum or consolidation on x-ray or CRP >5 mg/dL)
- Patients who have a nasopharyngeal swab for respiratory virus PCR test performed within 72 hours of admission for any of the 3 reasons
You may not qualify if…
- Patients with a clear other cause of acute heart failure (ex. ACS, bradycardia requiring a pacemaker, uncontrolled tachycardia, uncontrolled severe hypertension (SBP >180mmHg or DBP >110mmHg), haemoglobin <7g/dL or AHF precipitated by medication non-adherence)
- If the cause of pulmonary oedema is prominently attributed to exacerbation of CKD
- If there is a clear other source of infection that can explain the fever
Where it is running
- Seoul National University Bundang Hospital — Seongnam-si, Gyeonggi-do, South Korea (enrolling)
- Samsung medical center — Seoul, South Korea (enrolling)
- Seoul ST. Mary's Hospital — Seoul, South Korea (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.