Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy

Recruiting now · Not applicable

Conditions studied: Facet Joint Arthropathy, Pain, Osteoarthritis

In brief

This single-site, single-arm study evaluates the feasibility, safety, tolerability, and efficacy of trans-arterial embolization (TAE) using Embozene microparticles for treating facetogenic pain due to facet arthropathy (osteoarthritis of the facet joints) in the lumbar spine.

Key facts

Study ID

NCT06965452

Run by

Northwell Health

People needed

40

Starts

2025-08-12

Expected to finish

2026-08-01

Last updated by the study team

2025-08-19

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-85
• Confirmed diagnosis of spinal facet arthropathy on MRI OR CT
• Confirmed diagnosis of lumbosacral facetogenic pain based on diagnostic nerve blocks.
• Failed medical management of pain.
• Back pain persistent for at least 6 months
• Pain worse than at least 6/10 on a visual analog pain scale
• Failed at least one of either intra-articular injections of steroids/ anesthetics or neuro-ablative procedure.
• Maximum of 2 spinal levels of facetogenic pain in the lumbar and sacral spine (i.e. L4-5 and L5-S1).
• Modified Rankin Scale 0-2

You may not qualify if…

• - Pregnancy
• History of prior spinal embolization at the target level.
• History of surgery/ stenting of the aorta at the level of embolization.
• Severe allergic reaction to iodinated contrast (i.e. anaphylaxis)
• Creatinine > 1.5 mg/dl and/or creatinine clearance < 60 mL/min (except if patients is already on hemodialysis).
• Modified Rankin Scale >2
• Angiographic/ Procedural Exclusion Criterion: Vascular supply to the spinal cord from the vessels supplying the facet joints targeted for embolization.

Where it is running

• North Shore University Hospital — Manhasset, New York, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.