Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study

Recruiting now · Not applicable

Conditions studied: Cholangiocarcinoma, Extrahepatic, Cholangiocarcinoma of the Extrahepatic Bile Duct, Cholangiocarcinoma, Perihilar, Diagnosis, Raman Spectroscopy, Klatskin Tumor, Endoscopy, Biliary Stricture, Malignant Biliary Stricture

In brief

Diagnosis of extrahepatic cholangiocarcinoma is challenging because the yield of imaging and tissue sampling is limited. Raman spectroscopy is an optical method based on the analysis of scattered monochromatic light. Raman spectroscopy is able to provide a molecular 'fingerprint' of the tissue to determine its type. The aim of this pilot study was to develop a methodology for in vivo Raman spectroscopy in bile ducts to improve the current diagnostic capabilities of extrahepatic cholangiocarcinoma.

Key facts

Study ID

NCT06964425

Run by

University Hospital Olomouc

People needed

20

Starts

2023-02-04

Expected to finish

2025-07-30

Last updated by the study team

2025-07-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• person older than 18 years, who has known extrahepatic cholangiocarcinoma and is indicated for ERCP

You may not qualify if…

• disagreement with the study

Where it is running

• Peter Slodička — Olomouc, Olomouc Region, Czechia (enrolling)

Full record on ClinicalTrials.gov

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