Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort

Recruiting now

Conditions studied: Large Vessel Occlusion, Acute Ischemic Stroke

In brief

This multicenter, ambispective cohort study establishes a comprehensive multiomics biobank from five stroke centers, encompassing thrombi, intracranial blood, peripheral arterial/venous blood, and clinical-laboratory-imaging-follow-up data from patients with acute ischemic stroke with large vessel occlusion (AIS-LVO).

Key facts

Study ID

NCT06963489

Run by

First Affiliated Hospital of Wannan Medical College

People needed

500

Starts

2025-04-27

Expected to finish

2028-02-29

Last updated by the study team

2025-05-11

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age over 18 years.
• Patients with intracranial and extracranial large vessel occlusion ischemic stroke confirmed by cerebrovascular angiography.
• Availability of complete clinical and follow-up information required for the study.
• Availability of blood and/or thrombus biological samples.
• Voluntary written informed consent signed by the patient or their family (1) For retrospectively enrolled patients, a "broad informed consent" was signed at the time of sample collection. Upon enrollment into the cohort, a follow-up phone call was made to confirm the informed consent.
• (2) For prospectively enrolled patients, informed consent for this study was signed at the time of enrollment by the patient or their family.

You may not qualify if…

• Patients for whom biological samples cannot be obtained;
• Patients or their family members who refuse to sign the informed consent form.

Where it is running

• Baotou Central Hospital — Baotou, Inner Mongolia, China (enrolling)
• Affiliated Hospital of Shandong University of Traditional Chinese Medicine Hospital — Jinan, Shandong, China (enrolling)
• The First Affiliated Hospital of zhengzhou University — Henan, Zhengzhou, China (enrolling)
• Capital medical university of Beijing Tiantan Hospital — Beijing, China (enrolling)
• The First Affiliated Hospital of Shihezi University — Wuhu, Anhui, China

Full record on ClinicalTrials.gov

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