16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy

Recruiting now · Not applicable

Conditions studied: Pneumothorax, Pleural Effusion

In brief

The aim of the study is to evaluate postoperative pain in patients receiving a small-bore (16F) chest drain compared to those receiving the standard large-bore (24F) chest drain after minimally invasive pulmonary lobectomy and/or segmentectomy.

Key facts

Study ID

NCT06958848

Run by

University Hospital, Basel, Switzerland

People needed

124

Starts

2025-05-01

Expected to finish

2027-08-30

Last updated by the study team

2026-05-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Informed Consent signed by the patient (all sex and gender)
• Patients' age from ≥ 18 to no age limit at time of study inclusion
• American Society of Anaesthesiologists (ASA) physical status classification I to IV
• Patients with resectable non-small cell lung cancer (NSCLC) deemed operable by minimally invasive surgical technique.
• Minimally invasive anatomical lung resections under general anaesthesia: lobectomy, lobectomy with wedge resection, lobectomy combined with segmentectomy, segmentectomy with wedge resection, bilobectomy

You may not qualify if…

• Previous thoracic surgery on the same side within 3 months
• Lung cancer complicated with pleural empyema
• Patients with chronic pain who receive opioids/gabapentin/pregabalin
• Patients who consume opiates/benzodiazepines
• Congestive heart failure NYHA Class III or IV
• Liver cirrhosis Child-Pugh Class B and C
• Renal insufficiency requiring dialysis and/or estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2
• Patients with coagulopathy or bleeding disorders: von Willebrand disease, Hemophilia; Thrombocytopenia (<50 G/l), requiring platelet transfusion
• Patients with neuralgia
• Chest pain (site of surgery) without taking painkillers, measured by VAS while coughing > 10 mm
• Not consolidated rib fractures (in the last 3 months) on the side of surgical procedure
• Open anatomical lung resection, including pneumonectomy
• Insertion of 2 or more chest tubes
• Need for patient controlled intravenous anaesthesia or patient controlled epidural anaesthesia
• Patients intubated/sedated (not suitable due to difficulties to fill out the pain survey)

Where it is running

• University Hospital Basel — Basel, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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