A Prospective Study to Evaluate the Performance of a Real-time System in the Estimation of Colorectal Polyp Size

Recruiting now · Not applicable

Conditions studied: Colonic Polyps, CRC (Colorectal Cancer), Artificial Intelligence (AI)

In brief

Colorectal polyp size is related to the risk of exhibiting advanced histological features. Moreover, polyps larger than 10 mm are associated with an elevated risk of metachronous advanced neoplasia and colorectal cancer (CRC). Consequently, accurate measurement of polyp size, especially at the 10 mm threshold is critical for risk stratification and surveillance intervals. Furthermore, polyp size is also important for the choice of the appropriate resection procedures. Underestimation may lead to delayed diagnosis, thereby increasing the risk of colorectal cancer, while overestimation may result in unnecessary surveillance endoscopies.

Key facts

Study ID

NCT06957015

Run by

Chinese University of Hong Kong

People needed

278

Starts

2025-05-13

Expected to finish

2028-01-01

Last updated by the study team

2026-04-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects are eligible if:
• They have received colonoscopy for screening, surveillance or symptom investigation;
• Aged 18 years older or above;
• Written informed consent obtained.

You may not qualify if…

• Subjects are excluded if they have:
• Contraindication to colonoscopy (e.g. intestinal obstruction or perforation)
• Contraindication or conditions precluding polyp resection (e.g. active gastrointestinal bleeding, uninterrupted anticoagulation or dual antiplatelets)
• Advanced comorbid conditions (defined as American Society of Anesthesiologists grade 4 or above)

Where it is running

• Prince of Wales Hospital — Shatin, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

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