Effects of Asymmetries on Binaural-Hearing Abilities Across the Lifespan

Enrolling by invitation · Not applicable

Conditions studied: Aging, Hearing Loss, Hearing Asymmetry

In brief

Binaural hearing involves combining auditory information across the ears. With binaural hearing, listeners benefit from perceiving sounds from different spatial locations. This is critical in solving the "cocktail party problem" (i.e., understanding speech in the presence of competing background sounds and noise). As humans get older, hearing loss increases, binaural abilities decrease, and the cocktail party problem becomes increasingly difficult. This research studies the mechanisms underlying the impact of age and hearing loss on speech-perception in noise and cocktail-party listening situations. More specifically, the role of hearing asymmetries between the ears is investigated. The specific aims are to generate an audiological and binaural-hearing-focused dataset for a large cohort of participants that vary in hearing asymmetry, age, and hearing loss and to use machine learning to uncover complex associations and generate novel hypotheses relating audiometric variables and basic binaural-hearing abilities to the cocktail-party problem. Participants in this research will complete perceptual measures of hearing acuity and spatial hearing. Participants will also report on speech understanding under noisy and challenging listening conditions. This research may lead to improvements in audiological care and hearing interventions.

Key facts

Study ID

NCT06953700

Run by

University of Maryland, College Park

People needed

150

Starts

2024-06-17

Expected to finish

2026-05-01

Last updated by the study team

2025-05-01

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (18-80 years)
• No hearing asymmetry between ears (≤10 dB at any frequency) or, hearing asymmetry between ears >10 dB
• Native English speakers
• Primarily use oral language
• Sufficient corrected or uncorrected visual acuity (20/50 or better) to read large-font text

You may not qualify if…

• Acoustic tone-detection threshold >50 dB HL at any octave frequency (250-4000 Hz) in either ear (i.e., more than a moderate hearing loss)
• History of neurological disorders (e.g., stroke, Parkinson's disease) determined by self-report
• History of post-traumatic stress disorder or traumatic brain injury determined by self-report
• Possibility of acoustic neuroma, hearing asymmetry (>10 dB at three consecutive audiometric threshold frequencies)
• Montreal Cognitive Assessment (MoCA) score <22/30
• No oral language use
• Cochlear implant user
• Conductive hearing loss

Where it is running

• University of Maryland, College Park — College Park, Maryland, United States

Full record on ClinicalTrials.gov

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