Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair
Starting soon · Not applicable · Has a placebo group
Conditions studied: Hernia, Ventral, Pain Management
In brief
The purpose of this study is to determine whether using a QL block is better than placebo (a look-alike substance that contains no drug) in lowering the amount of opioids you need for pain relief in the first 24 hours and if it improves your recovery following a ventral hernia repair. Participants will be asked to complete a questionnaire before surgery and again at their 30-day follow up. You will also be asked to complete a pain diary 24 hours after surgery and attend a follow-up visit approximately 30 days after surgery. The following information will be collected from you or your medical record: 1. Pain medications given to you during surgery. 2. Pain medications prescribed to you after surgery, including medication name, dose, units, and frequency. 3. Pain levels during the first 24 hours after surgery. 4. Your total hospital length of stay after surgery. 5. Any complications that you may have experienced after surgery. 6. Demographic information, medical history as well as details about your hernia repair surgery.
Key facts
- Study ID
- NCT06953635
- Run by
- University of Tennessee Graduate School of Medicine
- People needed
- 70
- Starts
- 2025-06-01
- Expected to finish
- 2026-02-28
- Last updated by the study team
- 2025-05-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- >18 years of age
- Able to read and understand study procedures
- Willing to participate and sign an informed consent form
- Open approaches to ventral hernia repair
- Clean (CDC Class I), clean-contaminated (CDC Class II)
- Elective surgery
- Mesh placed in the retromuscular position
You may not qualify if…
- Dirty-Infected cases (CDC Class IV): Old traumatic wounds with retained devitalized tissue and those that involve existing clinical infection or perforated viscera
- Patient has a contraindication to receiving the drug and/or procedure: allergy/sensitivity to the drug, coagulopathy, abdominal wall infection at the drug administration site, systemic infection, anatomical distortion, neuropathy
- Emergent procedure
- Mesh not placed
Where it is running
- The University of Tennessee Medical Center — Knoxville, Tennessee, United States
Full record on ClinicalTrials.gov
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