At Home Ammonia Monitoring of Inborn Errors of Ammonia Metabolism
Recruiting now · Not applicable
Conditions studied: Urea Cycle Disorders, Organic Acidemias, Fatty Acid Oxidation Disorder, Ammonia; Metabolic Disorder
In brief
The goal of this observational study is to learn if people with certain ammonia metabolism disorders will measure their ammonia levels at home. The main question it aims to answer is: • Will participants measure their ammonia every day? Participants will be asked to: * Attend two in-person study visits at the clinic. * Measure temperature, heart rate, and blood oxygen every day. * Complete a short survey every day. * Measure ammonia every day.
Key facts
- Study ID
- NCT06953505
- Run by
- Sequitur Health Corp.
- People needed
- 30
- Starts
- 2025-09-23
- Expected to finish
- 2027-08-01
- Last updated by the study team
- 2026-05-27
Who can join
Age: 12 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Confirmed ammonia disorder such as
- Ornithine transcarbamylase deficiency
- Systemic primary carnitine deficiency
- Type I citrullinemia
- Argininosuccinic aciduria
- Isolated methylmalonic acidemia
- Type II citrullinemia
- Propionic acidemia
- Isovaleric acidemia
- Multiple acyl-CoA dehydrogenase deficiency
- Pyruvate carboxylase deficiency
- Argininemia (arginase deficiency)
- Carbamoyl phosphate synthase I deficiency
- Dihydrolipoamide dehydrogenase deficiency
- Lysinuric protein intolerance
- Hyperornithinemia-hyperammonemia-homocitrullinuria
- Carnitine-acylcarnitine translocase deficiency
- Carbonic anhydrase VA deficiency
- N-acetyl glutamate synthetase deficiency
- English Literacy
You may not qualify if…
- Incarcerated
- Presence of a non-inborn error of metabolism medical condition associated with abnormal ammonia metabolism (e.g., end stage liver disease).
- Unable to read in English
Where it is running
- Oregon Health & Science University — Portland, Oregon, United States (enrolling)
Full record on ClinicalTrials.gov
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