Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
Recruiting now · Not applicable
Conditions studied: Total Knee Arthroplasty, Functional Recovery, Aging, Physical Therapy
In brief
Patients experience dramatic quadriceps strength loss after total knee replacement, which contributes to persistent weakness and reduced long-term function after surgery. Neuromuscular electrical stimulation (NMES) reduces quadriceps weakness and improves patient function after knee replacement, but it is drastically underused in rehabilitation practice. This randomized trial will examine the effectiveness and feasibility of a comprehensive strategy for implementing neuromuscular electrical stimulation after knee replacement in two large healthcare organizations.
Key facts
- Study ID
- NCT06953375
- Run by
- University of Colorado, Denver
- People needed
- 3250
- Starts
- 2025-05-12
- Expected to finish
- 2029-04-01
- Last updated by the study team
- 2025-09-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Site Inclusion Criteria:
- UCHealth or Intermountain Health outpatient physical therapy clinic
- Patient Inclusion Criteria:
- Underwent primary unilateral TKA
- Attended outpatient rehabilitation at a participating clinic within 5 days after TKA
- Attended at least 3 total outpatient physical therapy visits in total
You may not qualify if…
- Patient Exclusion Criteria:
- NMES Contraindications [Patients with implanted cardiovascular cardiovertedefibrillator (ICD), active cancer, post-operative diagnosed deep vein thrombosis (DVT) in involved lower extremity]
- Previous lower extremity arthroplasty less than 12 weeks prior to scheduled TKA surgical date
Where it is running
- UCHealth — Aurora, Colorado, United States (enrolling)
- University of Colorado Denver, Anschutz — Aurora, Colorado, United States (enrolling)
- Intermountain Health — Murray, Utah, United States (enrolling)
Full record on ClinicalTrials.gov
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