Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease

Recruiting now

Conditions studied: Adult Congenital Heart Disease, Congenital Heart Disease, PTSD

In brief

The purpose of this study, entitled "Psychological trauma, post-traumatic stress disorder, and resilience in adults with congenital heart disease in a large population sample", is to evaluate for exposures during a lifetime with congenital heart disease that may be associated with higher likelihood of developing PTSD. Primary aim: \- Identify individual patient characteristics (medical, psychosocial, socioeconomic, etc.) that are associated with a diagnosis of PTSD. Secondary aims: * Calculate the prevalence of those meeting PTSD criteria in the ACHD population using the "gold standard" diagnostic clinician interview, while using the same data to validate a PTSD screening self-report survey in the ACHD population. * Determine the role of resilience in ACHD patients using a validated screening survey to assess its protective role toward PTSD. Hypotheses: * There are certain exposures (e.g. post-surgical pain, ICU delirium, bullying due to CHD) that are associated with a higher incidence and odds of meeting PTSD criteria. * "Gold standard" diagnostic interviews will most accurately estimate the prevalence of PTSD in ACHD which has been overestimated on prior screening-based studies, although the scope of the problem is still great. * Patients with a higher resilience score will show an association with a lower risk of PTSD.

Key facts

Study ID

NCT06952933

Run by

Dartmouth-Hitchcock Medical Center

People needed

1000

Starts

2025-09-01

Expected to finish

2026-08-01

Last updated by the study team

2026-03-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Congenital heart disease diagnosis, age >= 18 years
• Enrolled in CHI registry
• English proficiency for survey completion
• Access to an internet connection. Can be via computer or handheld device.

You may not qualify if…

• Any who opt out
• Age < 18 years
• No diagnosis of congenital heart disease
• Not enrolled in CHI registry/unable to access Internet

Where it is running

• Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire, United States (enrolling)
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Nationwide Children's Hospital — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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