Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

Recruiting now · Not applicable

Conditions studied: Peripheral Arterial Disease

In brief

The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease progression and the response to interventional treatment in PAD patients.

Key facts

Study ID

NCT06952543

Run by

Mayo Clinic

People needed

400

Starts

2025-03-14

Expected to finish

2029-08-30

Last updated by the study team

2026-05-05

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patient volunteers:
• Male and Female, ages 18 years old and up
• Symptom of claudication and suspected for PAD
• Scheduled for vascular testing.
• Healthy volunteers:
• Male and female, ages 18-75 years old and up
• Normal BMI
• No history of smoking, cardiovascular disease, or diabetes.

You may not qualify if…

• Patient volunteers:
• Patients with gangrene
• Patients having surgery or stent
• Patients with ulcer on their leg
• Any health condition that does not allow proper use of ultrasound scanning
• People considered in "vulnerable" populations.
• Healthy volunteers:
• Include volunteers with BMI not more than 30
• No history of smoking
• No history of (diabetes, hypertension, cardiovascular diseases)
• People considered in "vulnerable" populations.

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

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