Optimizing Aerobic Fitness in Older Adults

Recruiting now · Not applicable

Conditions studied: Aerobic Capacity, High Intensity Interval Training

In brief

Hospitalization and treatment for cardiovascular disease is one of the main contributors to disability in older adults. Moderate intensity continuous aerobic and resistance training have been the cornerstone of cardiac rehabilitation (CR) for decades to remediate hospital-acquired functional deficits, but some groups receive less or minimal functional benefit from this training. The proposed studies seek to optimize recovery of aerobic fitness and physical function among older cardiac patients using a novel high intensity training regimen with the long-term goal of reducing subsequent disability and improving clinical outcomes.

Key facts

Study ID

NCT06951620

Run by

University of Vermont Medical Center

People needed

114

Starts

2025-04-17

Expected to finish

2029-06-30

Last updated by the study team

2025-06-08

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• >65 years old
• ambulatory
• enrolled in CR at our center following a recent clinical diagnosis of myocardial infarction or percutaneous intervention will be recruited

You may not qualify if…

• have an active malignancy (excluding non-melanoma skin cancer or low grade prostate cancer under surveillance)
• unwilling to comply with the exercise prescription they may be assigned to
• have a submaximal performance on entry exercise tolerance test, defined as respiratory exchange ratio <1.0

Where it is running

• UVMMC Cardiac Rehabilitation — South Burlington, Vermont, United States (enrolling)

Full record on ClinicalTrials.gov

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