Acute Effects of THC in Older Adult
Recruiting now · Phase 1 · Has a placebo group
Conditions studied: Age-related Cognitive Decline
In brief
The primary objective of this study is to determine if increasing age confers greater vulnerability to the acute A) cognitive (e.g., memory, attention, psychomotor function), B) subjective (e.g., anxiogenic and rewarding effects), and C) cardiovascular (heart rate and blood pressure), effects of THC in adults \> 21 years old. The secondary aims of the study are to explore age-related acute effects of THC on electrophysiological indices of information processing (e.g., auditory steady-state response (ASSR), oddball paradigm \[P300\], and resting state cortical noise) and to determine age-related differences in the metabolism of THC.
Key facts
- Study ID
- NCT06948136
- Run by
- Yale University
- People needed
- 60
- Starts
- 2025-06-06
- Expected to finish
- 2027-11-01
- Last updated by the study team
- 2025-08-18
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: accepted.
Where it is running
- VA Connecticut Healthcare System — West Haven, Connecticut, United States (enrolling)
Full record on ClinicalTrials.gov
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