Study of BLU-808 in Healthy Adult Participants

Completed · Phase 1 · Has a placebo group

Conditions studied: Healthy Participants

In brief

This is a 3-part study. Parts 1 and 2 are randomized, double-blind, placebo-controlled investigations of single ascending doses (SAD) (Part 1) and multiple ascending doses (MAD) (Part 2) of orally administered BLU-808 in healthy adult participants. Part 2 will also include an evaluation of the effect of multiple doses of BLU-808 on the single-dose pharmacokinetics (PK) of midazolam. Part 3 is an open-label, 2-sequence, 2-period, food effect (FE) study in healthy adult participants.

Key facts

Study ID
NCT06948032
Run by
Blueprint Medicines Corporation
People needed
95
Starts
2024-08-07
Expected to finish
2025-01-21
Last updated by the study team
2025-04-28

Who can join

Age: 19 and older, up to 65. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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