Intertransverse Process Block to Improve Quality of Recovery and Pain Management in Adult Cardiac Surgical Patients
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Chronic Postsurgical Pain
In brief
The goal of this clinical trial is to evaluate the efficacy of intertransverse process block (ITPB) in improving quality of recovery and potentially preventing chronic postsurgical pain (CPSP) in adult patients undergoing elective cardiac surgery (e.g., coronary artery bypass graft \[CABG\], valve repair/replacement, or combined CABG/valve procedures). The main questions it aims to answer are: 1. To investigate the quality of recovery after cardiac surgery, and its analgesic efficacy in the immediate postoperative period 2. To investigate the efficacy of intertransverse process block (ITPB) on CPSP after cardiac surgery by determining the incidence of CPSP at 3 month, defined as persistent pain that was not present before surgery or that had different characteristics, and other possible causes of pain are excluded. 3. To investigate the efficacy of ITPB on the incidence of CPSP at 6 month, 12 month, and the pain interference (sensory and affective components, physical activities) at 3 month, 6 month and 12 month after surgery
Key facts
- Study ID
- NCT06946290
- Run by
- Chinese University of Hong Kong
- People needed
- 96
- Starts
- 2026-01-02
- Expected to finish
- 2028-01-02
- Last updated by the study team
- 2026-03-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- adult patients aged 18 or older
- undergoing elective CABG, valve repair/replacement, or combined CABG/valve procedure via sternotomy
You may not qualify if…
- Emergency surgery
- redo surgery
- history of chronic pain or being on chronic opioids/sedatives
- renal failure with an estimated glomerular filtration rate ≤30 ml/min (calculated by Cockcroft-Gault formula)
- re-operation within 24 hours after surgery
- intraoperative use of remifentanil
- inability to provide informed consent.
Where it is running
- Prince of Wales Hospital — Hong Kong, Hong Kong (enrolling)
Full record on ClinicalTrials.gov
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