Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function

Recruiting now · Not applicable

Conditions studied: Overactive Bladder (OAB)

In brief

This is a pilot study to assess using validated outcome measures how ingesting pumpkin seed oil extract supports patient bladder function in a United States population.

Key facts

Study ID: NCT06944392
Run by: Northwestern University
People needed: 40
Starts: 2025-04-11
Expected to finish: 2026-10-01
Last updated by the study team: 2026-04-23

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

All patients evaluated at Northwestern's IPHP who report bladder function consistent with overactive bladder (urinary urgency, with or without urinary frequency more than 8 times daily or nocturia, with or without urgency urinary incontinence) at their index visit, who are also willing to use a dietary supplement and not initiate additional behavioral, medication or procedural treatment for 12 weeks following pumpkin seed oil extract initiation.

You may not qualify if…

Patients with any of the following will be excluded from the study:
Use of other supplements that contain pumpkin seed oil
≥Stage 3 pelvic organ prolapse
Urinary post-void residual ≥150cc
Culture-proven urinary tract infection at time of study enrollment
Recurrent urinary tract infection
Neurogenic bladder
Abdominal or pelvic malignancy
Initiation of new overactive bladder medications or supplements during study period or in the 3 months immediately preceding study enrollment
History of surgery in the past 12 months for pelvic organ prolapse, stress urinary incontinence, urgency urinary incontinence, or fecal or flatal incontinence
Patient's primary language is not English

Where it is running

Northwestern University — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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