Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Down Syndrome

Recruiting now · Not applicable

Conditions studied: Down Syndrome

In brief

Down syndrome (DS) is caused by trisomy 21, or the presence of an extra copy of chromosome 21. A calibrated weight scale is used to measure participants' weight accurately. A stadiometer measures participants' height to the nearest millimeter. A flexible non-stretchable waist circumference tape is used to assess abdominal obesity. Body mass index (BMI, ratio of height and weight, expressed as kg/m2 6-Min Walk is a test to evaluate aerobic fitness level. Brisk Walk, a type of moderate intensity aerobic exercise can be an effective component of a weight loss program for overweight and obese children with Down syndrome. The aim of this study to compare the effects of aerobic exercise alone versus aerobic exercise combined with a low calorie diet, to provide insights into optimal inte A randomized controlled trial will be conducted. The study will be conducted at Rehab Clinic, Lahore in a total duration of 10 months. Sample size will be 22. There will be two study groups, Group I: Aerobic Exercise with Low calorie diet and Group II: Aerobic Exercise without Low calorie diet. Non-Probability Convenient sampling technique will be used to collect the data.

Key facts

Study ID

NCT06943170

Run by

Riphah International University

People needed

22

Starts

2025-02-15

Expected to finish

2025-07-31

Last updated by the study team

2025-04-24

Who can join

Age: 8 and older, up to 16. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age (8-16) years.
• Both Genders (Male and Female).
• BMI-for-age percentile (at or above 85th percentile is overweight, and at or above 95th percentile is considered as obese)
• Children with generally stable health condition, without significant co-morbidities that might affect diet or exercise interventions.
• Consent form signed by parents, along with written approval by the physician.

You may not qualify if…

• History of any previous medical disease.
• Previous Participation in any Weight Loss Exercise Program.
• Participants following any specific diet plan from last 6 months.
• Exclusion of children on medication that could affect weight or metabolism.
• Children with physical disabilities that prevent them from safely participating in aerobic exercise.
• Children with dietary restrictions or food allergies.
• Children with severe cognitive impairments that prevent them from engaging in exercise program.

Where it is running

• Jannat Arshad — Lahore, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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