Relationship Between Mouth Opening and Masseter Elasticity in Oral Cancer

Recruiting now

Conditions studied: Oral Cancer

In brief

The study aims to assess the hardness of masticatory muscles in post-surgical oral cancer patients using strain elastography ultrasound, calculating the masseter elasticity index and exploring its association with maximum interincisal mouth opening. Furthermore, the study incorporates exercise training to analyze whether changes in masseter hardness can serve as an objective indicator for predicting the improvement of trismus.

Key facts

Study ID

NCT06941727

Run by

National Taiwan University Hospital

People needed

10

Starts

2025-05-16

Expected to finish

2026-12-31

Last updated by the study team

2026-05-18

Who can join

Age: 20 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Newly diagnosed oral cancer patients who are scheduled to receive cancer-related treatments (e.g., oral cancer surgery, radiotherapy, chemotherapy, or chemoradiotherapy).
• Age between 20 and 65 years.

You may not qualify if…

• Could not communicate.
• Had any disorder that could influence movement performance.

Where it is running

• National Taiwan University — Taipei, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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