Living With Guillain-Barré Syndrome as Children.
Recruiting now
Conditions studied: Guillain Barré Syndrome, Guillain-Barré Syndrome (GBS)
In brief
The goal of this qualitative observational study is to explore the lived experience and psychological aftermath of children who were affected by Guillain-Barré Syndrome (GBS) two to five years earlier. GBS is a rare and acute neurological condition, and while motor recovery is generally good in children, residual symptoms such as fatigue, pain, anxiety, or depression may persist and impact quality of life. The main questions it aims to answer are: How do children experience and recall their illness and recovery after GBS? What psychological or contextual factors might contribute to emotional distress or depressive symptoms in the years following the disease? Participants will: Be children aged 10 or older who had GBS two to five years prior. Participate in a 45-60-minute semi-structured individual interview during a routine follow-up visit. Respond to a screening questionnaire for depressive symptoms (Children's Depression Inventory or Beck Depression Inventory Fast Screen). Undergo a brief clinical examination to assess any remaining physical sequelae. Interviews will be audio recorded, transcribed verbatim, and pseudonymized. Thematic reflexive analysis will be performed following Braun and Clarke's methodology. Recruitment will continue until theoretical saturation is reached (approximately 25 participants expected) across two centers (Toulouse and Montpellier). This study aims to generate new insights into pediatric psychological outcomes after GBS, in order to improve acute care and follow-up, and potentially guide future mental health support for affected children.
Key facts
- Study ID
- NCT06940908
- Run by
- University Hospital, Toulouse
- People needed
- 25
- Starts
- 2025-05-05
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-05-08
Who can join
Age: 10 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Children or adolescents aged 10 years or older at the time of the interview
- History of Guillain-Barré syndrome (GBS) diagnosed in childhood
- Time since acute episode: between 2 and 5 years
- Sufficient mastery of the French language to participate in a semi-structured interview
- Consent of the participant and, for minors, parental consent
You may not qualify if…
- Presence of a neurological disease other than GBS that may interfere with participation or interpretation of data
- Severe cognitive impairment preventing the child or adolescent from engaging in the interview
Where it is running
- University Hospital Toulouse — Toulouse, Occitanie, France (enrolling)
- University Hospital of Montpellier — Montpellier, Occitanie, France
Full record on ClinicalTrials.gov
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