Chloride Imbalance in Preterm Infants

Recruiting now

Conditions studied: Bronchopulmonary Dysplasia (BPD), Mortality Prediction, Chloride Disorder

In brief

In adults and children low or high blood chloride levels are linked to the risk of death. The aim of this observational study is to determine whether there is a relationship between low or high blood chloride levels and the risk of death or long-term lung problems. We will also learn the risk factors and associated conditions of high or low blood chloride levels. We will include infants born before 32 weeks of pregnancy or have a birth weight of less than 1500 grams in the study. The main question it aims to answer is: Is there a relationship between low or high blood chloride levels in the first 4-6 weeks of life and risk of death or long-term lung problems in premature babies? We will examine the medical reports of babies who were followed up in neonatal intensive care unit over the past 5 years.

Key facts

Study ID

NCT06940856

Run by

Kanuni Sultan Suleyman Training and Research Hospital

People needed

500

Starts

2025-05-15

Expected to finish

2027-12-15

Last updated by the study team

2026-08-06

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Infants born <32 weeks PMA or <1500 grams
• Infants admitted to NICU within the first 24 hours

You may not qualify if…

• Infants with major congenital anomalies
• Infants with chromosomal anomalies
• Infants who have undergone enterostomy operation
• Infants admitted to NICU after the first 24 hours

Where it is running

• Kanuni Sultan Suleyman Education and Research Hospital — Istanbul, Turkey, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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