Exclude or Expose in Irritable Bowel Syndrome: What Works for Whom and How?

Recruiting now · Not applicable

Conditions studied: Irritable Bowel Syndrome (IBS), Intestinal Diseases, Gastrointestinal Disease

In brief

This research project will assess how two treatments for irritable bowel syndrome (one dietary and one behavioral) work and for whom. This will be done by assessing moderators (what treatment works for who and in what context) and mediators (how treatment works). Investigators will also assess how the diet and behavioral treatments affect IBS symptoms during treatment. Participants will be randomized to either: i. A FODMAP diet online program that focuses on modifying the consumption of foods high or moderate in fermentable carbohydrates (FODMAPS) to manage IBS symptoms. or, ii. An Exposure-based Cognitive Behavioral Therapy (E-CBT) online program for IBS that focuses on changing symptom-related behaviors which are known to worsen IBS symptoms.

Key facts

Study ID
NCT06940596
Run by
University of Melbourne
People needed
235
Starts
2025-05-22
Expected to finish
2028-04-01
Last updated by the study team
2026-05-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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