Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
Recruiting now · Not applicable
Conditions studied: Metastatic Colorectal Cancer (mCRC)
In brief
The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.
Key facts
- Study ID
- NCT06938971
- Run by
- Rigshospitalet, Denmark
- People needed
- 150
- Starts
- 2025-05-16
- Expected to finish
- 2030-05-01
- Last updated by the study team
- 2026-05-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (≥18 years of age) schduled to undergo first-line chemotherapy for the treatment of metastatic colorectal cancer.
You may not qualify if…
- Pregnancy.
- A life expectancy of < 6 months.
- Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology.
- ECOG (Eastern Cooperative Oncology Group) performance status > 2.
- Inability to understand the Danish or English language.
- Engagement in structured moderate-to-high aerobic exercise training for >30 min >1 times/week for the past 3 months at the time of inclusion.
Where it is running
- Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet — Copenhagen, Denmark (enrolling)
- Herlev and Gentofte Hospital — Herlev, Denmark (enrolling)
- North Zealand University Hospital, Hillerød — Hillerød, Denmark (enrolling)
- Zealand University Hospital, Roskilde — Roskilde, Denmark (enrolling)
Full record on ClinicalTrials.gov
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