How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study
Recruiting now · Not applicable
Conditions studied: Bleeding, Hip Fracture, Delirium - Postoperative
In brief
The goal of this clinical trial is to investigate whether early detection of bleeding and prompt blood transfusions can help prevent delirium in patients aged 75 and older who are admitted to the hospital with hip fractures. The main question the trial aims to answer is: Do patients aged 75 and older with hip fractures benefit from earlier treatment of anemia (low blood count) to reduce the risk of delirium? Researchers will compare early diagnosis and treatment of bleeding with standard care to determine if it helps lower the risk of developing delirium. Participants will: Undergo blood tests, have their vital signs monitored, and be screened for delirium three times a day for the first 48 hours after surgery. Receive blood transfusions promptly if their hemoglobin levels fall below a specified threshold. Attend a follow-up visit at 30 days to assess cognitive function and overall quality of life. Attend another follow-up at 90 days to evaluate hospital readmissions and survival.
Key facts
- Study ID
- NCT06938789
- Run by
- University of Aarhus
- People needed
- 198
- Starts
- 2025-04-24
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-05-22
Who can join
Age: 75 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Hip fracture
You may not qualify if…
- Pathological hip fracture
- Periprosthtic fracture
- Unable to speak or understand Danish
- Does not wish to recieve blood transfusion
- If the investigator finds the patient unable to cooperate to the study (e.g. in case of severe dementia and externalizing behaviour)
Where it is running
- Gødstrup Hospital, Department of internal medicine — Herning, Central Jutland, Denmark (enrolling)
- Aarhus University Hospital — Aarhus, Central Jutland, Denmark
Full record on ClinicalTrials.gov
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