Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI

Recruiting now · Not applicable

Conditions studied: Mild Cognitive Impairment

In brief

Mild Cognitive Impairment (MCI) is defined as an impairment in a single cognitive function, usually memory, other than normal cognitive decline with age, that does not fulfil dementia criteria. Finger movements have been shown to stimulate the sensory-motor and cognitive parts of the cerebral cortex, as well as the supplementary motor area, Broca's area, premotor cortex, and prefrontal cortex, all of which contribute to movement skills. Asymmetrical hand and finger movements done concurrently were proven to improve cognitive processes and cerebral blood flow more than movements performed with one hand.

Key facts

Study ID

NCT06935812

Run by

Eastern Mediterranean University

People needed

106

Starts

2025-04-29

Expected to finish

2026-09-24

Last updated by the study team

2026-05-19

Who can join

Age: 50 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Participants who are between 50-75 years of age
• Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria,
• Who has the Montreal Cognitive Assessment score between 13-26,
• Who has the Quick Mild Cognitive Impairment screen score between 48-67,
• Who has Instrumental Activities of Daily Living Scale score ≥6/8,
• Who says yes to "Do you have a memory problem?" question,
• Who can walk independently without using any walking aids

You may not qualify if…

• Participants who have any musculoskeletal disorders that may cause balance and gait disorders,
• Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies),
• Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)),
• Who has daltonism and
• Who attends any exercise program last 6 months will not be included in this study.

Where it is running

• Eastern Mediterranean University — Famagusta, Eyalet/Yerleşke, Cyprus (enrolling)

Full record on ClinicalTrials.gov

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