The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer

Recruiting now · Not applicable

Conditions studied: Thyroid Nodule, Thyroid Cancer

In brief

The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is: • What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)? Participants will undergo a set of pre-procedural scans of the target thyroid nodule and undergo the RFA procedure/intervention. Then, participants will partake in three follow-up appointments at 4 weeks, 6 months, and 12 months post-procedure as per standard of care.

Key facts

Study ID

NCT06929650

Run by

University Health Network, Toronto

People needed

40

Starts

2023-04-20

Expected to finish

2025-12-31

Last updated by the study team

2025-04-16

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients with:
• Nodule less than or equal to 2cm in size
• a. Specifically: Bethesda 5/6
• Their age is ≥18 years and ≤100 years
• Able to provide written consent
• Able to attend required follow-ups as per the protocol

You may not qualify if…

• Patients <18 years old
• Pregnant women
• Any concern for invasive or metastatic thyroid cancer
• Previously treated for thyroid cancer

Where it is running

• University Health Network — Toronto, Ontario, Canada (enrolling)

Full record on ClinicalTrials.gov

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