Frequency of Occurrence and Risk Factors of Postoperative Nausea and Vomiting During Elective C-section Under Spinal Anesthesia With Preventive Medication

Recruiting now

Conditions studied: Nausea and Vomiting, Postoperative, Cesarean Delivery, Spinal Anesthesia, Antiemetic Therapy

In brief

The aim of this study is to learn about the incidence and risk factors of nausea and vomiting during planned caesarean section under spinal anesthesia. The main question it aims to answer is : What are the incidence and risks factors of postoperative nausea and vomiting (NV) during planned caesarean section under spinal anesthesia with administration of intrathecal morphine and multimodal antiemetic prophylaxis ? Patients who will be managed according to the standard protocol in use in the department will have to answer specific questions about NV in the post-interventional recovery room and on 2 further visits in the first 24 hours post-caesarean section.

Key facts

Study ID: NCT06927830
Run by: University of Liege
People needed: 400
Starts: 2025-03-19
Expected to finish: 2026-04-01
Last updated by the study team: 2025-04-15

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

Any patient requiring elective caesarean section under spinal anesthesia, at a gestational age >37 weeks of amenorrhea in the context of a single-fetal pregnancy.

You may not qualify if…

Failure to understand the French language; Contraindication to locoregional anesthesia; Nausea and/or vomiting in the 24 hours preceding the procedure; Type 1 or type 2 insulin-requiring non-gestational diabetes; Allergy or contraindication to one of the products used in the usual management protocol; Severe preeclampsia; Height <150 cm

Where it is running

CHU de Liège - site de Notre-Dame des Bruyères — Chenée, Belgium (enrolling)
Hôpital de la Citadelle - site Citadelle — Liège, Belgium

Full record on ClinicalTrials.gov

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