Human Genes and Microbiota in Early Life
Recruiting now
Conditions studied: Host and Microbiome, Pregnancy Outcomes, Pregnancy Complications, Neurodevelopmental Disorders, Immune Development, Childhood Obesity, Type 2 Diabetes
In brief
The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life and their interaction with the host on maternal-offspring health consequences in later life in the born in Guangzhou cohort study in China. Identification of the effect of microbiota in early life, as well as environmental factors and microbe-host interaction, will lead to a better understanding of disease pathogenesis and provide a foundation for targeted mechanistic investigation into the consequences of microbial-host crosstalk for long-term health. It also can result in new strategies to predict and prevent diseases in later life.
Key facts
- Study ID
- NCT06926166
- Run by
- Guangzhou Women and Children's Medical Center
- People needed
- 20000
- Starts
- 2019-04-01
- Expected to finish
- 2038-12-31
- Last updated by the study team
- 2025-04-13
Who can join
Age: any. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Pregnant women with < 20 weeks of gestation Pregnant women intended to eventually deliver in Guangzhou Women and Children's medical center Permanent residengts of families intended to remain in Guangzhou with their child for ≥3 years
You may not qualify if…
- Refuses to have blood and stool samples stored at Born in Guangzhou cohort study Biobank.
Where it is running
- Guangzhou Women and Children's Medical Center, China — Guangzhou, China (enrolling)
Full record on ClinicalTrials.gov
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