Identification of Specific Molecular Signatures in Pediatric, Adolescent, and Young Adult Rhabdomyosarcoma Through Spatial Proteome Analysis Using Mass Spectrometry

Recruiting now

Conditions studied: Rhabdomyosarcoma

In brief

This non-interventional study aims to develop spatial proteomics for analyzing small FFPE tumor samples in rhabdomyosarcoma. It will identify molecular signatures linked to tumor regions, subtypes, survival, and treatment resistance, using pre-existing samples and data.

Key facts

Study ID

NCT06924463

Run by

Lille University

People needed

20

Starts

2025-03-13

Expected to finish

2026-02-28

Last updated by the study team

2025-04-11

Who can join

Age: any, up to 25. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 0 and 25 years at the time of initial diagnosis
• Diagnosis of rhabdomyosarcoma confirmed histologically
• Care at the Oscar Lambret Center between January 2005 and November 2024
• No objection to the re-use of data and biological samples collected as part of care for research activities.

You may not qualify if…

• Unavailability of biological sample in FFPE from biopsy and/or surgical specimen for diagnosis at Centre Oscar Lambret;
• Patient under guardianship or trusteeship.

Where it is running

• Oscar Lambret Center — Lille, Nord, France (enrolling)

Full record on ClinicalTrials.gov

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