Study of Alloknesia in Atopic Dermatitis

Recruiting now

Conditions studied: Atopic Dermatosis, Alloknesie

In brief

Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological conditions. Alloknesia occurs mainly in the context of chronic pruritus. Consequently, patients suffering from chronic pruritus frequently perceive light touch sensations as pruritic, which can be particularly unpleasant and alter human interactions and quality of life on a daily basis. However, the epidemiology and burden of alloknesia have never been studied, whatever the cause of chronic pruritus.Atopic dermatitis is one of the main diseases causing chronic itching, and patients frequently complain of alloknesia. In this study, the investigators are studying the frequency of alloknesia in patients with atopic dermatitis and measuring the consequences of alloknesia in these patients.

Key facts

Study ID

NCT06923202

Run by

University Hospital, Brest

People needed

160

Starts

2026-02-10

Expected to finish

2027-02-10

Last updated by the study team

2026-06-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years
• No opposition from the patient
• Diagnosis of atopic dermatitis more than 6 months old

You may not qualify if…

• Patients who are physically or mentally unable to complete the questionnaires.
• Patients on systemic treatment for 1 month or more
• Refusal to participate
• Patients under legal protection (guardianship, curatorship)
• Patients under court protection

Where it is running

• CHU d'Angers — Angers, France (enrolling)
• CHU de Brest — Brest, France (enrolling)
• CHD Vendée — La Roche-sur-Yon, France (enrolling)
• Groupe Hospitalier Bretagne Sud — Lorient, France (enrolling)
• CHU de Nantes Hôtel-Dieu — Nantes, France (enrolling)
• CHU de Rennes — Rennes, France (enrolling)
• CHU de Tours — Tours, France (enrolling)
• CH Bretagne Atlantique — Vannes, France (enrolling)

Full record on ClinicalTrials.gov

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