Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)

Starting soon

Conditions studied: Cardiac Amyloidosis, Transthyretin Amyloidosis

In brief

This study aims to determine the positive predictive value of incidental cardiac uptake on bone scintigraphy for diagnosing transthyretin cardiac amyloidosis, in patients who underwent scintigraphy for reasons other than suspected amyloidosis. The study is an observational, descriptive, multicenter, national study using retrospective data from routine care. Patients with incidental cardiac uptake will be recalled for further diagnostic assessment.

Key facts

Study ID

NCT06921408

Run by

University Hospital, Lille

People needed

57

Starts

2026-09-01

Expected to finish

2027-12-01

Last updated by the study team

2026-05-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (≥ 18 years)
• Patients who underwent bone scintigraphy with 99mTc-HMDP/DPD/PYP for any indication
• Incidental cardiac uptake (Perugini grade ≥2) confirmed by a nuclear medicine specialist

You may not qualify if…

• Patients under legal protection
• Patients refusing the reuse of their data after individual information

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.