Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder
Recruiting now · Not applicable
Conditions studied: Borderline Personality Disorder, Narcissism, Obsessive Compulsive Personality Disorder, Personality Disorder
In brief
The goal of this clinical trial is to evaluate whether a dimensional adaptation of Good Psychiatric Management (called GPM-extended) is more effective than classic Good Psychiatric Management (GPM) in treating adult patients with borderline personality disorder (BPD). Briefly, the GPM-extended model integrates elements from existing adaptations of GPM for narcissistic and obsessive-compulsive personality disorders. It aims to provide a more personalized and dimensional approach to treatment, tailored to each patient's specific personality dysfunction and interpersonal triggers. The main questions it aims to answer are: * Does GPM-extended improve overall BPD symptom severity more than classic GPM after one year of treatment? * Does GPM-extended lead to better outcomes in related clinical domains (e.g., personality functioning, emotional regulation, social functioning...) ? Researchers will compare two groups: * Patients treated in a center using the GPM-extended program. * Patients treated in a center using the classic GPM program. In each group, patients will receive weekly outpatient psychiatric care for one year. In terms of evaluation, patients will be evaluated at baseline, 4 months, 8 months, and 1 year. They will undergo both clinician-administered and self-report assessments to measure BPD symptoms and other relevant psychological dimensions. This study hopes to contribute to the development of dimensional evidence-based treatments for personality disorders.
Key facts
- Study ID
- NCT06913738
- Run by
- AddiPsy
- People needed
- 154
- Starts
- 2024-06-19
- Expected to finish
- 2029-12-01
- Last updated by the study team
- 2025-04-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (≥18 years old)
- Diagnosis of borderline personality disorder according to the SCID-II (≥5 out of 9 criteria)
- Provision of written informed consent
- Affiliated with or beneficiary of the French national health insurance system
You may not qualify if…
- Age under 18 years
- Presence of a comorbid psychotic disorder, intellectual disability, severe antisocial traits, major substance use disorder incompatible with intensive therapy without abstinence, anorexia nervosa with somatic risk, or bipolar disorder in acute manic phase
- Individuals under legal protection (e.g., guardianship or legal safeguard)
- Individuals unable to cooperate or complete self- or clinician-administered questionnaires
- Individuals not affiliated with or not beneficiaries of the French national health insurance system
Where it is running
- Clinique Caradoc — Bayonne, France (enrolling)
- Addipsy — Lyon, France (enrolling)
Full record on ClinicalTrials.gov
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