GWAS to Identify Predictive Genetic Factors for the Success of Dietary Intervention in the Treatment of IBS Symptoms

Recruiting now

Conditions studied: Irritable Bowel Syndrome (IBS), Genome-wide Association Study, Single Nucleotide Polymorphisms, Mediterranean Diet, FODMAP Diet

In brief

This is a GWAS that aims to identify possible single nucleotide polymorphisms (SNPs) that are associated with the response in a combined dietary pattern low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols and Meditteranean diet (MED-LFD) in a small group of patients with Irritable Bowel Syndrome (IBS).

Key facts

Study ID

NCT06912828

Run by

Attikon Hospital

People needed

100

Starts

2024-09-15

Expected to finish

2027-02-15

Last updated by the study team

2025-04-06

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Fulfillment of the Rome IV criteria for IBS
• Provision of written informed consent.
• Commitment of availability throughout the study period.
• IBS-SSS > 175

You may not qualify if…

• Any concomitant disease requiring specialized nutrition (e.g. renal failure, diabetes, celiac disease, cerebrovascular disease of the central nervous system, major surgical cavity).
• Pregnancy.
• Breastfeeding.

Where it is running

• Attikon General University Hospital of Athens — Athens, Greece (enrolling)

Full record on ClinicalTrials.gov

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