Hypoxia, Appetite, and Energy Intake in Young Female Adults

Recruiting now · Not applicable

Conditions studied: Hypoxia, Altitude, Appetite, Energy Intake

In brief

The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are: * Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake? * Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simulated high-altitude to a control normoxia (sea-level) condition to see if exposure to low oxygen levels independently affect appetite and energy intake. Participants will: * Visit the laboratory for a preliminary screening session to assess eligibility. * Undergo two randomized, single-blind, experimental sessions consisting of six hours of passive exposure to normoxia or hypoxia in a climate-controlled chamber. * Consume foods provided from a curated list, served in ad libitum quantities, after leaving the laboratory to assess post-exposure energy intake.

Key facts

Study ID

NCT06912230

Run by

University of Ottawa

People needed

10

Starts

2024-11-13

Expected to finish

2025-12-01

Last updated by the study team

2025-04-04

Who can join

Age: 18 and older, up to 30. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• English or French speaking
• Ability to provide informed consent

You may not qualify if…

• History or evidence of chronic disease
• Current use of hypolipemic medication
• Current use of hormonal contraceptives
• Current use of antidepressants
• Current use of anticoagulants
• Ongoing smoking status
• Experiencing pregnancy, puerperium, or irregular menstrual cycles

Where it is running

• Behavioural and Metabolic Research Unit, School of Human Kinetics, Faculty of Health Sciences, University of Ottawa — Ottawa, Ontario, Canada (enrolling)

Full record on ClinicalTrials.gov

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