Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients
Recruiting now · Not applicable
Conditions studied: Sepsis, Emergency Care, Microcirculation
In brief
Despite early treatment, the deterioration and mortality of sepsis patients remains high. A possible explanation could be persistent tissue hypoperfusion, or undetected in the early phase despite the normalization of macro-hemodynamic parameters. This interventional study evaluates the impact of measuring microcirculation parameters by nurses on patient prognosis through early initiation of vascular filling.
Key facts
- Study ID
- NCT06910891
- Run by
- University Hospital, Limoges
- People needed
- 556
- Starts
- 2025-09-20
- Expected to finish
- 2027-03-28
- Last updated by the study team
- 2025-11-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- Admitted to the Emergency Department for suspected Sepsis for less than 6 hours according to international Sepsis-3 definitions (high probability of infection defined by a fever greater than or equal tol to 38.3°C with a suspected infectious source + Score NEWS 2 greater than or equal to 2)
- Affiliated to a social security system
- Having agreed to participate in this study
You may not qualify if…
- Patient with arterial hypotension (SBP ≤ 100 mmHg) on admission
- Patient having already received a 500mL filling test over 30 minutes
- Patients moribund according to the investigator
- Pregnancy or breastfeeding
- Patient under guardianship, curatorship or safeguard of justice
Where it is running
- Brive Hospital — Brivé, France (enrolling)
- Guéret Hospital — Guéret, France (enrolling)
- Limoges University Hospital — Limoges, France (enrolling)
- Saint Junien Hospital — Saint-Junien, France (enrolling)
- Tulle Hospital — Tulle, France (enrolling)
- Ussel Hospital — Ussel, France (enrolling)
Full record on ClinicalTrials.gov
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