A Study of Chios Mastic Water in Dyspepsia
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Dyspepsia
In brief
Chios mastic is a natural product with strong antimicrobial, anti-inflammatory and antioxidant properties, and well-established benefits for dyspeptic disorders. The aim of the present study is to investigate the effectiveness of a natural aqueous extract of Chios mastic (mastic water), a by-product of Chios mastic processing, in the management of dyspepsia. This will be a 3-month randomized double-blind controlled clinical trial in adults with dyspepsia. Participants will be blindly randomized to an intervention group, which will receive 600 mL/d of a carbonated beverage enriched with Chios mastic water (0.2%), or a control group, which will receive 600 mL/d of an identical placebo beverage with no active ingredients. Participants will be evaluated in terms of anthropometric indices, lifestyle habits, severity of dyspepsia-related gastrointestinal symptoms, quality of life, as well as biochemical markers, both pre- and post-intervention.
Key facts
- Study ID
- NCT06909890
- Run by
- Harokopio University
- People needed
- 60
- Starts
- 2025-07-10
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2025-09-15
Who can join
Age: 30 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 30-60 years old.
- Body mass index of 20-35 kg/m2.
- Presence of dyspepsia.
You may not qualify if…
- Presence of chronic diseases (e.g. diabetes mellitus, cancer, cardiovascular, hepatic, renal, respiratory, chronic inflammatory and psychiatric diseases).
- Presence of other chronic gastrointestinal diseases (e.g. gastroesophageal reflux, inflammatory bowel disease and celiac disease).
- Use of immunosuppressants, anti-inflammatories, antibiotics and corticosteroids.
- Use of dietary supplements or other products with Chios mastic.
- Excessive alcohol consumption (>210 g and >140 g of ethanol per week for men and women, respectively).
- Currently on a weight-loss diet or recent (within 6 months) significant change in lifestyle habits.
- Pregnancy or breast feeding (for women)
Where it is running
- Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University of Athens — Kallithea, Attica, Greece (enrolling)
Full record on ClinicalTrials.gov
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