Prevalence of Ethnic Neutropenia and Duffy Null Phenotype in Neonates

Recruiting now

Conditions studied: Neutropenia (Low White Blood Cell Count)

In brief

This is a prospective observational study designed to assess the prevalence of the Duffy null phenotype (associated with ethnic neutropenia) in neonates born at Kaplan Medical Center. Blood samples will be collected from umbilical cords (non-invasively) to evaluate Duffy antigen expression. Data on ethnicity, perinatal factors, and routine blood counts at 9-12 months (when available) will also be collected to correlate phenotype with absolute neutrophil count (ANC).

Key facts

Study ID

NCT06908616

Run by

Kaplan Medical Center

People needed

1000

Starts

2024-10-08

Expected to finish

2027-12-31

Last updated by the study team

2025-04-06

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Neonates born at Kaplan Medical Center between 1.9.2024 and 31.12.2025
• Parental informed consent obtained
• Umbilical cord blood available for routine testing

You may not qualify if…

• None

Where it is running

• Kaplan Medical Center — Rehovot, Israel, Israel (enrolling)

Full record on ClinicalTrials.gov

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